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IMG 7289 CTP 201 was a global open label Phase 2b study of bomedemstat IMG 7289 MK 3543 taken once daily for 24 weeks in patients with ET resistant to or intolerant of at least one standard treatment NCT04254978
Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185
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IMG 7289 Ferreting Out The Fun
IMG 7289 Ferreting Out The Fun
IMG 7289 CTP 102 is a global open label Phase 1 2 study evaluating bomedemstat dosed once daily in MF patients NCT03136185 Data from this ongoing study are presented
Aims IMG 7289 CTP 102 is an ongoing global open label Phase 2 study evaluating bomedemstat dosed QD in MF patients NCT03136185 Key eligibility criteria include patients intolerant refractory resistant or inadequately controlled by approved therapy and platelet count 100 x 109 L Key objectives are safety and reduction of spleen
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IMG 7289
IMG 7289
A phase 2 study of bomedemstat IMG 7289 a lysine specific demethylase 1 LSD1 inhibitor for the treatment of later stage myelofibrosis MF Presented at 2020 European Hematology
IMG 7289 CTP 102 is an ongoing multi center open label study that recently transitioned from a Phase 1 2a dose range finding study to a Phase 2b study of IMG 7289 administered orally once daily in adult patients with intermediate 2 or high risk MF resistant to or intolerant of ruxolitinib
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IMG 7289
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https://ashpublications.org/blood/article/140...
Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185
https://ashpublications.org/blood/article/138...
IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978
Lysine specific demethylase 1 LSD1 is a histone demethylase critical for self renewal potential of malignant stem cells and progenitor maturation Bomedemstat is an oral LSD1 inhibitor clinically active in patients with MPNs IMG 7289 CTP 102 is a global open label Phase 2 study evaluating bomedemstat dosed in MF patients NCT03136185
IMG 7289 CTP 201 is a global open label Phase 2b study of bomedemstat taken once daily for 24 weeks in patients with ET who are resistant to or intolerant of at least one SOC treatment NCT04254978
IMG 7289 IL AasgutenIL Aasguten
IMG 7289 Dreesch7
IMG 7289 YouTube
IMG 7289 YouTube
IMG 7289 GiraGira
IMG 7289 Alexander Flickr
IMG 7289 Alexander Flickr
IMG 7289 Don Wan Flickr